Recombinant Human KPNA2, His-tagged

• Cat.No.: KPNA2-1049H

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Importins are involved in nuclear import and belong to a seperate class of Ran-GTP binding proteins. Importin α itself does not interact with the nuclear pore complex but functions as an adaptor that binds importin β. It is required to mediate binding of substrates to their receptors. Importin α binds directly to the nuclear localization signal of substrates.MW = 57.86 kDa.
• Purity: > 95% by SDS-PAGE.
• Form: Liquid. Supplied in 50 mM Tris-HCl pH 7.5, and 2 mM DTE.
• Storage: Quality guaranteed for 12 months. Store at -80°C.Avoid freeze / thaw cycles.
• Usage: For in vitro use only.

Gene Information

• Gene Name: KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) [ Homo sapiens ]
• Synonyms: karyopherin alpha 2 (RAG cohort 1, importin alpha 1); QIP2; RCH1; IPOA1; SRP1alpha; KPNA2; karyopherin alpha 2; pendulin; RAG cohort 1; importin alpha 1; importin alpha 2 importin-alpha-P1; Karyopherin subunit alpha-2; RAG cohort protein 1
• Gene ID: 3838
• mRNA Refseq: NM_002266
• Protein Refseq: NP_002257
• MIM: 600685
• UniProt ID: P52292
• Chromosome Location: 17q24.2
• Function: histone deacetylase binding; nuclear localization sequence binding; protein binding; protein transporter activity