Recombinant Human KRT2 Protein (Cys7-Leu160), His tagged

• Cat.No.: KRT2-2413H
• Product Overview: Recombinant human KRT2 (Cys7-Leu160) protein fused with His tag was expressed in E. coli.

Specification

• Description: The mRNA and protein expression of KRT2 was highly expressed in brown skin in comparison with that in white skin.After transfection with KRT2 in alpaca melanocytes, the relative mRNA and protein expression of KRT2, microphthalmia-associtated transcription factor (MITF), tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1) in alpaca skin melanocytes was increased with significant differences; a further result was the increase of melanin production. KRT2 functions in alpaca hair color formation, which offered an essential theoretical basis for further exploration of the role of melanogenesis.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 15.42 kDa
• Protein Length: Cys7-Leu160
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: KRT2 keratin 2 [ Homo sapiens (human) ]
• Official Symbol: KRT2
• Synonyms: KRT2; keratin 2; keratin 2A (epidermal ichthyosis bullosa of Siemens), KRT2A; keratin, type II cytoskeletal 2 epidermal; epidermal ichthyosis bullosa of Siemens; KRTE; keratin-2e; cytokeratin-2e; keratin-2 epidermis; type-II keratin Kb2; epithelial keratin-2e; K2e; CK-2e; KRT2A; KRT2E; MGC116967; MGC116968
• Gene ID: 3849
• mRNA Refseq: NM_000423
• Protein Refseq: NP_000414
• MIM: 600194
• UniProt ID: P35908