Recombinant Human KSR1 Protein, GST-tagged

• Cat.No.: KSR1-4796H
• Product Overview: Human KSR1 full-length ORF ( AAI67812.1, 1 a.a. - 762 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: Enables 14-3-3 protein binding activity; ATP binding activity; and protein C-terminus binding activity. Involved in positive regulation of MAPK cascade. Located in endoplasmic reticulum and membrane. Part of protein-containing complex. Implicated in breast adenocarcinoma. Biomarker of breast cancer.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 83.9 kDa
• AA Sequence: MNEAKVKETLRRCGASGDECGRLQY ALTCLRKVTGLGGEHKEDSSWSSLD ARRESGSGPSTDTLSAASLPWPPGS SQLGRAGNSAQGPRSISVSALPASD SPTPSFSEGLSDTCIPLHASGRLTP RALHSFITPPTTPQLRRHTKLKPPR TPPPPSRKVFQLLPSFPTLTRSKSH ESQLGNRIDDVSSMRFDLSHGSPQM VRRDIGLSVTHRFSTKSWLSQVCHV CQKSMIFGVKCKHCRLKCHNKCTKE APACRISFLPLTRLRRTESVPSDIN NPVDRAAEPHFGTLPKALTKKEHPP AMNHLDSSSNPSSTTSSTPSSPAPF PTSSNPSSATTPPNPSPGQRDSRFN FPAAYFIHHRQQFIFPVPSAGHCWK CLLIAESLKENAFNISAFAHAAPLP EAADGTRLDDQPKADVLEAHEAEAE EPEAGKSEAEDDEDEVDDLPSSRRP WRGPISRKASQTSVYLQEWDIPFEQ VELGEPIGQGRWGRVHRGRWHGEVA IRLLEMDGHNQDHLKLFKKEVMNYR QTRHENVVLFMGACMNPPHLAIITS FCKGRTLHSFVRDPKTSLDINKTRQ IAQEIIKGMGYLHAKGIVHKDLKSK NVFYDNGKVVITDFGLFGISGVVRE GRRENQLKLSHDWLCYLAPEIVREM TPGKDEDQLPFSKAADVYAFGTVWY ELQARDWPLKNQAAEASIWQIGSGE GMKRVLTSVSLGKEVSEILSACWAF DLQERPSFSLLMDMLEKLPKLNRRL SHPGHFWKSAEL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KSR1 kinase suppressor of ras 1 [ Homo sapiens (human) ]
• Official Symbol: KSR1
• Synonyms: KSR1; kinase suppressor of ras 1; KSR; RSU2; kinase suppressor of Ras 1; EC 2.7.11.1
• Gene ID: 8844
• mRNA Refseq: https://www.ncbi.nlm.nih.gov/nuccore/NM_014238.2
• Protein Refseq: https://www.ncbi.nlm.nih.gov/protein/NP_055053.1
• MIM: https://omim.org/entry/601132
• UniProt ID: https://www.uniprot.org/uniprotkb/Q8IVT5/entry