| Description : |
This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
47.8 kDa |
| AA Sequence : |
MAEAVLIDLFGLKLNSQKNCHQTLL KTLNAVQYHHAAKAKFLCIMCCSNI SYERDGEQDNCEIETSNGLSALLEE FEIVSCPSMAATLYTIKQKIDEKNL SSIKVIVPRHRKTLMKAFIDQLFTD VYNFEFEDLQVTFRGGLFKQSIEIN VITAQELRGIQNEIETFLRSLPALR GKLTIITSSLIPDIFIHGFTTRTGG ISYIPTLSSFNLFSSSKRRDPKVVV QENLRRLANAAGFNVEKFYRIKTHH SNDIWIMGRKEPDSYDGITTNQRGV TIAALGADCIPIVFADPVKKACGVA HAGWKGTLLGVAMATVNAMIAEYGC SLEDIVVVLGPSVGPCCFTLPRESA EAFHNLHPACVQLFDSPNPCIDIRK ATRILLEQGGILPQNIQDQNQDLNL CTSCHPDKFFSHVRDGLNFGTQIGF ISIKETRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
