Recombinant Human LAG3 Protein, Met-tagged, Alexa Fluor 647 conjugated
Cat.No. : | LAG3-467HAF647 |
Product Overview : | Alexa Fluor 647 conjugated recombinant human LAG3 (P18627) (Met1-Arg440) was expressed with an initial Met. |
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Description : | LAG3, also known as CD223 and Lymph centigradeyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo. |
Source : | HEK293 |
Species : | Human |
Tag : | initial Met |
Form : | Lyophilized |
Molecular Mass : | 44.7 kDa |
Protein length : | Met1-Arg440, 412 |
N-terminal Sequence Analysis : | Val 29 |
Endotoxin : | < 1.0 EU/ μg protein as determined by the LAL method. |
Purity : | > 90 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 647 via amines Excitation = 650 nm Emission = 668 nm |
Storage : | Samples are stable for up to twelve months from date of receipt at -70 centigrade. Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS,pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | LAG3 lymphocyte-activation gene 3 [ Homo sapiens ] |
Official Symbol : | LAG3 |
Synonyms : | LAG3; lymphocyte-activation gene 3; lymphocyte activation gene 3 protein; CD223; |
Gene ID : | 3902 |
mRNA Refseq : | NM_002286 |
Protein Refseq : | NP_002277 |
MIM : | 153337 |
Products Types
◆ Recombinant Protein | ||
LAG3-676H | Recombinant Human LAG3 Protein, IgG2a Fc-tagged | +Inquiry |
LAG3-225H | Recombinant Human LAG3 Protein (ECD), His-tagged(C-ter) | +Inquiry |
Lag3-1727M | Recombinant Mouse Lag3 Protein, His-tagged | +Inquiry |
LAG3-15H | Active Recombinant Human LAG3 protein(Met1-Leu450), mFc-tagged | +Inquiry |
LAG3-677H | Recombinant Human LAG3 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
LAG3-941RCL | Recombinant Rat LAG3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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