Recombinant Human LARGE1 protein, His & GST-tagged
| Cat.No. : | LARGE1-1601H |
| Product Overview : | Recombinant Human LARGE1 aa. (Thr25~Ala178 (Accession # O95461)) fused with N-terminal His & GST tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
| Description : | This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe cognitive disability and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His & GST |
| Form : | Freeze-dried powder |
| Molecular Mass : | Predicted Molecular Mass: 47.0kDa |
| Protein length : | Thr25~Ala178 (Accession # O95461) |
| Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
| Purity : | >95% |
| Applications : | SDS-PAGE; WB; ELISA; IP. |
| Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
| Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
| Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
| Isoelectric Point : | 7 |
| Gene Name : | LARGE1 LARGE xylosyl- and glucuronyltransferase 1 [ Homo sapiens (human) ] |
| Official Symbol : | LARGE1 |
| Synonyms : | LARGE1; LARGE xylosyl- and glucuronyltransferase 1; LARGE; MDC1D; MDDGA6; MDDGB6; LARGE xylosyl- and glucuronyltransferase 1; glycosyltransferase-like protein LARGE1; acetylglucosaminyltransferase-like 1A; acetylglucosaminyltransferase-like protein |
| Gene ID : | 9215 |
| mRNA Refseq : | NM_004737.5 |
| Protein Refseq : | NP_004728.1 |
| UniProt ID : | O95461 |
Products Types
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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