Active Recombinant Human LDLR protein, Fc-tagged

• Cat.No.: LDLR-335H
• Product Overview: Active Recombinant Human LDLR protein(P01130) is produced by our Mammalian expression system and the target gene encoding Ala22-Arg788 is expressed with a human IgG1 Fc tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 22-788 aa
• Form: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
• Bio-activity: Immobilized Recombinant Human LDL R (C-Fc) at 5μg/ml (100 μl/well) can bind Recombinant Human PCSK9 (D374Y,C-6His). The ED50 of Recombinant Human PCSK9 (D374Y,C-6His) is 39.17 ng/ml.
• Molecular Mass: 111.7 KDa
• Endotoxin: < 1 EU/µg as determined by LAL test.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
• Concentration: 0.1-1.0 mg/mL. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: LDLR low density lipoprotein receptor [ Homo sapiens ]
• Official Symbol: LDLR
• Synonyms: LDLR; low density lipoprotein receptor; low-density lipoprotein receptor; familial hypercholesterolemia; LDL receptor; low-density lipoprotein receptor class A domain-containing protein 3; FH; FHC; LDLCQ2
• Gene ID: 3949
• mRNA Refseq: NM_000527
• Protein Refseq: NP_000518
• MIM: 606945
• UniProt ID: P01130