Recombinant Human LILRB5 protein, His-Avi-tagged

• Cat.No.: LILRB5-023H
• Product Overview: Recombinant Human LILRB5 Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Arg18-His456.

Specification

• Description: LILRB5, also known as CD85c andLIR-8, belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Ig-like domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 may act as receptor for class I MHC antigens.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 49.9 kDa.Due to glycosylation, the protein migrates to 67-72 KDa based on Bis-Tris PAGE result.
• Protein length: Arg18-His456
• Endotoxin: Less than 0.1 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: LILRB5 leukocyte immunoglobulin like receptor B5 [ Homo sapiens (human) ]
• Official Symbol: LILRB5
• Synonyms: CD85 antigen-like family member C; CD85c antigen; CD85c; Leukocyte immunoglobulin-like receptor 8; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains); LILRB5; LIR8; LIR-8; LIR8CD85C; LIR-8leukocyte immunoglobulin-like receptor subfamily B member 5; member 5
• Gene ID: 10990
• mRNA Refseq: NM_001081442.3
• Protein Refseq: NP_001074911.2
• MIM: 604814
• UniProt ID: O75023