| Description : |
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
49.2 kDa |
| Protein Length : |
590 |
| AA Sequence : |
MTLTLSVLICLGLSVGPRTCVQAGT LPKPTLWAEPASVIARGKPVTLWCQ GPLETEEYRLDKEGLPWARKRQNPL EPGAKAKFHIPSTVYDSAGRYRCYY ETPAGWSEPSDPLELVATGFYAEPT LLALPSPVVASGGNVTLQCDTLDGL LTFVLVEEEQKLPRTLYSQKLPKGP SQALFPVGPVTPSCRWRFRCYYYYR KNPQVWSNPSDLLEILVPGVSRKPS LLIPQGSVVARGGSLTLQCRSDVGY DIFVLYKEGEHDLVQGSGQQPQAGL SQANFTLGPVSRSHGGQYRCYGAHN LSPRWSAPSDPLDILIAGLIPDIPA LSVQPGPKVASGENVTLLCQSWHQI DTFFLTKEGAAHPPLCLKSKYQSYR HQAEFSMSPVTSAQGGTYRCYSAIR SYPYLLSSPSYPQELVVSGPSGDPS LSPTGSTPTPGPEDQPLTPTGLDPQ SGLGRHLGVVTGVSVAFVLLLFLLL FLLLRHRHQSKHRTSAHFYRPAGAA GPEPKDQGLQKRASPVADIQEEILN AAVKDTQPKDGVEMDARAAASEAPQ DVTYAQLHSLTLRREATEPPPSQER EPPAEPSIYAPLAIH |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
