Recombinant Human LIMA1 Protein, GST-tagged

• Cat.No.: LIMA1-4020H
• Product Overview: Human EPLIN full-length ORF ( AAH01247, 1 a.a. - 598 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 91.52 kDa
• AA Sequence: MENCLGESRHEVEKSEISENTDASG KIEKYNVPLNRLKMMFEKGEPTQTK ILRAQSRSASGRKISENSYSLDDLE IGPGQLSSSTFDSEKNESRRNLELP RLSETSIKDRMAKYQAAVSKQSSST NYTNELKASGGEIKIHKMEQKENVP PGPEVCITHQEGEKISANENSLAVR STPAEDDSRDSQVKSEVQQPVHPKP LSPDSRASSLSESSPPKAMKFQAPA RETCVECQKTVYPMERLLANQQVFH ISCFRCSYCNNKLSLGTYASLHGRI YCKPHFNQLFKSKGNYDEGFGHRPH KDLWASKNENEEILERPAQLANARE TPHSPGVEDAPIAKVGVLAASMEAK ASSQQEKEDKPAETKKLRIAWPPPT ELGSSGSALEEGIKMSKPKWPPEDE ISKPEVPEDVDLDLKKLRRSSSLKE RSRPFTVAASFQSTSVKSPKTVSPP IRKGWSMSEQSEESVGGRVAERKQV ENAKASKKNGNVGKTTWQNKESKGE TGKRSKEGHSLEMENENLVENGADS DEDDNSFLKQQSPQEPKSLNWSSFV DNTFAEEFTTQNQKSQDVELWEGEV VKELSVEEQIKRNRYYDEDEDEE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LIMA1 LIM domain and actin binding 1 [ Homo sapiens ]
• Official Symbol: LIMA1
• Synonyms: LIMA1; LIM domain and actin binding 1; LIM domain and actin-binding protein 1; epithelial protein lost in neoplasm beta; EPLIN; 1110021C24Rik; sterol regulatory element binding protein 3; SREBP3; FLJ38853; MGC131726
• Gene ID: 51474
• mRNA Refseq: NM_001113547
• Protein Refseq: NP_001107019
• MIM: 608364
• UniProt ID: Q9UHB6