| Description : |
This gene encodes a protein belonging to the L-type lectin group of type 1 membrane proteins, which function in the mammalian early secretory pathway. These proteins contain luminal carbohydrate recognition domains, which display homology to leguminous lectins. Unlike other proteins of the group, which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes, the protein encoded by this gene is a non-cycling resident protein of the ER, where it functions as a cargo receptor for glycoproteins. It is proposed to regulate exchange of folded proteins for transport to the Golgi and exchange of misfolded glycoproteins for transport to the ubiquitin-proteasome pathway. [provided by RefSeq, Apr 2016] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
39.7 kDa |
| AA Sequence : |
MAATLGPLGSWQQWRRCLSARDGSR MLLLLLLLGSGQGPQQVGAGQTFEY LKREHSLSKPYQGVGTGSSSLWNLM GNAMVMTQYIRLTPDMQSKQGALWN RVPCFLRDWELQVHFKIHGQGKKNL HGDGLAIWYTKDRMQPGPVFGNMDK FVGLGVFVDTYPNEEKQQERVFPYI SAMVNNGSLSYDHERDGRPTELGGC TAIVRNLHYDTFLVIRYVKRHLTIM MDIDGKHEWRDCIEVPGVRLPRGYY FGTSSITGDLSDNHDVISLKLFELT VERTPEEEKLHRDVFLPSVDNMKLP EMTAPLPPLSGLALFLIVFFSLVFS VFAIVIGIILYNKWQEQSRKRFYTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
