Recombinant Human LONP1 Protein, GST-tagged

• Cat.No.: LONP1-4737H
• Product Overview: Human LONP1 full-length ORF ( NP_004784.2, 1 a.a. - 959 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 132.9 kDa
• AA Sequence: MAASTGYVRLWGAARCWVLRRPMLA AAGGRVPTAAGAWLLRGQRTCDASP PWALWGRGPAIGGQWRGFWEASSRG GGAFSGGEDASEGGAEEGAGGAGGS AGAGEGPVITALTPMTIPDVFPHLP LIAITRNPVFPRFIKIIEVKNKKLV ELLRRKVRLAQPYVGVFLKRDDSNE SDVVESLDEIYHTGTFAQIHEMQDL GDKLRMIVMGHRRVHISRQLEVEPE EPEAENKHKPRRKSKRGKKEAEDEL SARHPAELAMEPTPELPAEVLMVEV ENVVHEDFQVTEEVKALTAEIVKTI RDIIALNPLYRESVLQMMQAGQRVV DNPIYLSDMGAALTGAESHELQDVL EETNIPKRLYKALSLLKKEFELSKL QQRLGREVEEKIKQTHRKYLLQEQL KIIKKELGLEKDDKDAIEEKFRERL KELVVPKHVMDVVDEELSKLGLLDN HSSEFNVTRNYLDWLTSIPWGKYSN ENLDLARAQAVLEEDHYGMEDVKKR ILEFIAVSQLRGSTQGKILCFYGPP GVGKTSIARSIARALNREYFRFSVG GMTDVAEIKGHRRTYVGAMPGKIIQ CLKKTKTENPLILIDEVDKIGRGYQ GDPSSALLELLDPEQNANFLDHYLD VPVDLSKVLFICTANVTDTIPEPLR DRMEMINVSGYVAQEKLAIAERYLV PQARALCGLDESKAKLSSDVLTLLI KQYCRESGVRNLQKQVEKVLRKSAY KIVSGEAESVEVTPENLQDFVGKPV FTVERMYDVTPPGVVMGLAWTAMGG STLFVETSLRRPQDKDAKGDKDGSL EVTGQLGEVMKESARIAYTFARAFL MQHAPANDYLVTSHIHLHVPEGATP KDGPSAGCTIVTALLSLAMGRPVRQ NLAMTGEVSLTGKILPVGGIKEKTI AAKRAGVTCIVLPAENKKDFYDLAA FITEGLEVHFVEHYREIFDIAFPDE QAEALAVER
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LONP1 lon peptidase 1, mitochondrial [ Homo sapiens ]
• Official Symbol: LONP1
• Synonyms: LONP1; lon peptidase 1, mitochondrial; protease, serine, 15 , PRSS15; lon protease homolog, mitochondrial; hLON; LonHS; PIM1; serine protease 15; protease, serine, 15; Lon protease-like protein; hLON ATP-dependent protease; mitochondrial lon peptidase 1; mitochondrial lon protease-like protein; mitochondrial ATP-dependent protease Lon; LON; LONP; PRSS15; MGC1498
• Gene ID: 9361
• mRNA Refseq: NM_004793
• Protein Refseq: NP_004784
• MIM: 605490
• UniProt ID: P36776