Recombinant Human LOX Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: LOX-6669H
• Product Overview: LOX MS Standard C13 and N15-labeled recombinant protein (NP_002308) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 46.8 kDa
• AA Sequence: MRFAWTVLLLGPLQLCALVHCAPPA AGQQQPPREPPAAPGAWRQQIQWEN NGQVFSLLSLGSQYQPQRRRDPGAA VPGAANASAQQPRTPILLIRDNRTA AARTRTAGSSGVTAGRPRPTARHWF QAGYSTSRAREAGASRAENQTAPGE VPALSNLRPPSRVDGMVGDDPYNPY KYSDDNPYYNYYDTYERPRPGGRYR PGYGTGYFQYGLPDLVADPYYIQAS TYVQKMSMYNLRCAAEENCLASTAY RADVRDYDHRVLLRFPQRVKNQGTS DFLPSRPRYSWEWHSCHQHYHSMDE FSHYDLLDANTQRRVAEGHKASFCL EDTSCDYGYHRRFACTAHTQGLSPG CYDTYGADIDCQWIDITDVKPGNYI LKVSVNPSYLVPESDYTNNVVRCDI RYTGHHAYASGCTISPYTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: LOX lysyl oxidase [ Homo sapiens (human) ]
• Official Symbol: LOX
• Synonyms: LOX; lysyl oxidase; protein-lysine 6-oxidase; MGC105112
• Gene ID: 4015
• mRNA Refseq: NM_002317
• Protein Refseq: NP_002308
• MIM: 153455
• UniProt ID: P28300