Recombinant Human LRRC15 protein, His-Avi-tagged

• Cat.No.: LRRC15-066H
• Product Overview: Recombinant Human LRRC15 Protein is expressed from Expi293 with a His and Avi Tag at the C-terminal. It contains Tyr22-Gly538.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Tyr22-Gly538
• Description: The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 60.7 kDa.Due to glycosylation, the protein migrates to 70-80 KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 1 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: LRRC15
• Official Symbol: LRRC15
• Synonyms: LIB, LRRC15
• Gene ID: 131578
• mRNA Refseq: NM_001135057.3
• Protein Refseq: NP_001128529.2
• UniProt ID: Q8TF66