- Human(2)
- Mouse(2)
- Rat(1)
- Rhesus Macaque(1)
Recombinant Human LRRC8C Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | LRRC8C-2672H |
| Product Overview : | LRRC8C MS Standard C13 and N15-labeled recombinant protein (NP_115646) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 92.4 kDa |
| AA Sequence : | MIPVTEFRQF SEQQPAFRVL KPWWDVFTDY LSVAMLMIGV FGCTLQVMQD KIICLPKRVQ PAQNHSSLSN VSQAVASTTP LPPPKPSPAN PITVEMKGLK TDLDLQQYSF INQMCYERAL HWYAKYFPYL VLIHTLVFML CSNFWFKFPG SSSKIEHFIS ILGKCFDSPW TTRALSEVSG EDSEEKDNRK NNMNRSNTIQ SGPEGSLVNS QSLKSIPEKF VVDKSTAGAL DKKEGEQAKA LFEKVKKFRL HVEEGDILYA MYVRQTVLKV IKFLIIIAYN SALVSKVQFT VDCNVDIQDM TGYKNFSCNH TMAHLFSKLS FCYLCFVSIY GLTCLYTLYW LFYRSLREYS FEYVRQETGI DDIPDVKNDF AFMLHMIDQY DPLYSKRFAV FLSEVSENKL KQLNLNNEWT PDKLRQKLQT NAHNRLELPL IMLSGLPDTV FEITELQSLK LEIIKNVMIP ATIAQLDNLQ ELSLHQCSVK IHSAALSFLK ENLKVLSVKF DDMRELPPWM YGLRNLEELY LVGSLSHDIS RNVTLESLRD LKSLKILSIK SNVSKIPQAV VDVSSHLQKM CIHNDGTKLV MLNNLKKMTN LTELELVHCD LERIPHAVFS LLSLQELDLK ENNLKSIEEI VSFQHLRKLT VLKLWHNSIT YIPEHIKKLT SLERLSFSHN KIEVLPSHLF LCNKIRYLDL SYNDIRFIPP EIGVLQSLQY FSITCNKVES LPDELYFCKK LKTLKIGKNS LSVLSPKIGN LLFLSYLDVK GNHFEILPPE LGDCRALKRA GLVVEDALFE TLPSDVREQM KTETRTRPLE QKLISEEDLA ANDILDYKDD DDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | LRRC8C leucine rich repeat containing 8 VRAC subunit C [ Homo sapiens (human) ] |
| Official Symbol : | LRRC8C |
| Synonyms : | LRRC8C; leucine rich repeat containing 8 family, member C; AD158; FAD158; volume-regulated anion channel subunit LRRC8C; factor for adipocyte differentiation 158; hypothetical protein AD158; leucine rich repeat containing 8 family member C; leucine rich repeat containing 8C; leucine-rich repeat-containing protein 8C |
| Gene ID : | 84230 |
| mRNA Refseq : | NM_032270 |
| Protein Refseq : | NP_115646 |
| MIM : | 612889 |
| UniProt ID : | Q8TDW0 |
◆ Recombinant Protein
| Lrrc8c-162M | Recombinant Mouse Lrrc8c Protein, MYC/DDK-tagged | +Inquiry |
| LRRC8C-2568R | Recombinant Rhesus monkey LRRC8C Protein, His-tagged | +Inquiry |
| LRRC8C-9298M | Recombinant Mouse LRRC8C Protein | +Inquiry |
| LRRC8C-3480R | Recombinant Rat LRRC8C Protein | +Inquiry |
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◆ Lysates
| LRRC8C-4621HCL | Recombinant Human LRRC8C 293 Cell Lysate | +Inquiry |
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LRRC32LRRC8DLRRC29LRRC4CLRRC2LRRC7LRRC71LRRC73LRRC16ALRRC72LRRC38LRRC39LRRC40LRRC41LRRC43LRRC48LRRC4BLRRC52LRRC57LRRC58LRRC8BLRRC8ELRRC10LRRC14LRRC19LRRC20LRRC23LRRC25LRRC26LRRC28LRRC3LRRC31LRRC34LRRC36LRRC37A3LRRC37BLRRC6LRRC61LRRC63LRRC66LRRC1LRRC4LRRC15LRRC17LRRC33LRRC16BLRRC18LRRC27LRRC3BLRRC45LRRC46LRRC47LRRC56LRRC55LRRC59LRRC70LRRC8CLRRC50LRRC30LRRC37A2LRRC49Lrrc51LRRC68Lrrc10bLrrc14bLrrc24LRRC3CLrrc42Lrrc69Lrrc8aLrrc9
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