Recombinant Human LRWD1 Protein, GST-tagged LRWD1-4621H

Recombinant Human LRWD1 Protein, GST-tagged

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Recombinant Human LRWD1 Protein, GST-tagged

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Cat.No. : LRWD1-4621H
Product Overview : Human LRWD1 full-length ORF ( NP_690852.1, 1 a.a. - 647 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 97.3 kDa
AA Sequence : MGPLSARLLMQRGRP KSDRLGKIRSLDLSG LELLSEHLDPKLLCR LTQLQELDLSNNHLE TLPDNLGLSHLRVLR CANNQLGDVTALCQF PKLEELSLEGNPFLT VNDNLKVSFLLPTLR KVNGKDASSTYSQVE NLNRELTSRVTAHWE KFMATLGPEEEAEKA QADFVKSAVRDVRYG PESLSEFTQWRVRMI SEELVAASRTQVQKA NSPEKPPEAGAAHKP RARLAALKRPDDVPL SLSPSKRACASPSAQ VEGSPVAGSDGSQPA VKLEPLHFLQCHSKN NSPQDLETQLWACAF EPAWEEGATSQTVAT CGGEAVCVIDCQTGI VLHKYKAPGEEFFSV AWTALMVVTQAGHKK RWSVLAAAGLRGLVR LLHVRAGFCCGVIRA HKKAIATLCFSPAHE THLFTASYDKRIILW DIGVPNQDYEFQASQ LLTLDTTSIPLRLCP VASCPDARLLAGCEG GCCCWDVRLDQPQKR RVCEVEFVFSEGSEA SGRRVDGLAFVNEDI VASKGSGLGTICLWS WRQTWGGRGSQSTVA VVVLARLQWSSTELA YFSLSACPDKGIVLC GDEEGNVWLYDVSNI LKQPPLLPAALQAPT QILKWPQPWALGQVV TKTMVNTVVANASFT YLTALTDSNIVAIWG RM
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : LRWD1 leucine-rich repeats and WD repeat domain containing 1 [ Homo sapiens ]
Official Symbol : LRWD1
Synonyms : LRWD1; leucine-rich repeats and WD repeat domain containing 1; leucine-rich repeat and WD repeat-containing protein 1; CENP 33; centromere protein 33; DKFZp434K1815; ORCA; origin recognition complex associated; ORC-associated protein; origin recognition complex-associated protein; CENP-33;
Gene ID : 222229
mRNA Refseq : NM_152892
Protein Refseq : NP_690852
UniProt ID : Q9UFC0

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