Recombinant Human Lysine (K)-specific Demethylase 4C, GST-tagged
Cat.No. : | KDM4C-428H |
Product Overview : | Recombinant Human JMJD2C (amino-acids 2-372), with N-terminal GST tag expressed in aBaculovirus infected Sf9cell expression system. MW = 69 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | KDM4C-428H |
Description : | Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene. This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. |
Source : | Sf9 cell. |
Purity : | >80%. |
Application : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Formulated In : | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT. |
Stability : | >6 months at –80°C. |
Gene Name : | KDM4C lysine (K)-specific demethylase 4C [ Homo sapiens ] |
Synonyms : | KDM4C; lysine (K)-specific demethylase 4C; GASC1; JHDM3C; JMJD2C; FLJ25949; KIAA0780; bA146B14.1; jumonji domain containing 2C; gene amplified in squamous cell carcinoma 1; JmjC domain-containing histone demethylation protein 3C; EC 1.14.11.- |
Gene ID : | 23081 |
mRNA Refseq : | NM_001146694 |
Protein Refseq : | NP_001140166 |
MIM : | 605469 |
UniProt ID : | Q9H3R0 |
Chromosome Location : | 9p24.1 |
Function : | iron ion binding; molecular_function; oxidoreductase activity; oxidoreductase activity, acting on single donors with; incorporation of molecular oxygen, incorporation of two atoms of oxygen; protein binding; zinc ion binding |
Products Types
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KDM4C-0529H | Recombinant Human KDM4C Protein (M1-K347), Tag Free | +Inquiry |
KDM4C-4780M | Recombinant Mouse KDM4C Protein, His (Fc)-Avi-tagged | +Inquiry |
KDM4C-0530H | Recombinant Human KDM4C Protein (M1-K347), His tagged | +Inquiry |
◆ Lysates | ||
KDM4C-4994HCL | Recombinant Human KDM4C 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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