Recombinant Human LZTFL1 Protein, GST-tagged

• Cat.No.: LZTFL1-4526H
• Product Overview: Human LZTFL1 full-length ORF ( NP_065080.1, 1 a.a. - 299 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 61 kDa
• AA Sequence: MAELGLNEHHQNEVINYMRFARSKR GLRLKTVDSCFQDLKESRLVEDTFT IDEVSEVLNGLQAVVHSEVESELIN TAYTNVLLLRQLFAQAEKWYLKLQT DISELENRELLEQVAEFEKAEITSS NKKPILDVTKPKLAPLNEGGTAELL NKEILRLQEENEKLKSRLKTIEIQA TNALDEKSKLEKALQDLQLDQGNQK DFIKAQDLSNLENTVAALKSEFQKT LNDKTENQKSLEENLATAKHDLLRV QEQLHMAEKELEKKFQQTAAYRNMK EILTKKNDQIKDLRKRLAQYEPED
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LZTFL1 leucine zipper transcription factor-like 1 [ Homo sapiens ]
• Official Symbol: LZTFL1
• Synonyms: LZTFL1; leucine zipper transcription factor-like 1; leucine zipper transcription factor-like protein 1; FLJ36386
• Gene ID: 54585
• mRNA Refseq: NM_020347
• Protein Refseq: NP_065080
• MIM: 606568
• UniProt ID: Q9NQ48