Recombinant Human LZTFL1 Protein, GST-tagged

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Recombinant Human LZTFL1 Protein, GST-tagged

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Cat.No. : LZTFL1-4526H
Product Overview : Human LZTFL1 full-length ORF ( NP_065080.1, 1 a.a. - 299 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2013]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 61 kDa
AA Sequence : MAELGLNEHH QNEVINYMRF ARSKRGLRLK TVDSCFQDLK ESRLVEDTFT IDEVSEVLNG LQAVVHSEVE SELINTAYTN VLLLRQLFAQ AEKWYLKLQT DISELENREL LEQVAEFEKA EITSSNKKPI LDVTKPKLAP LNEGGTAELL NKEILRLQEE NEKLKSRLKT IEIQATNALD EKSKLEKALQ DLQLDQGNQK DFIKAQDLSN LENTVAALKS EFQKTLNDKT ENQKSLEENL ATAKHDLLRV QEQLHMAEKE LEKKFQQTAA YRNMKEILTK KNDQIKDLRK RLAQYEPED
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : LZTFL1 leucine zipper transcription factor-like 1 [ Homo sapiens ]
Official Symbol : LZTFL1
Synonyms : LZTFL1; leucine zipper transcription factor-like 1; leucine zipper transcription factor-like protein 1; FLJ36386;
Gene ID : 54585
mRNA Refseq : NM_020347
Protein Refseq : NP_065080
MIM : 606568
UniProt ID : Q9NQ48

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