Recombinant Human M6PR Protein, MYC/DDK-tagged

• Cat.No.: M6PR-179H
• Product Overview: Recombinant human M6PR protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.

Specification

• Description: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. [UniProtKB/Swiss-Prot Function]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 27.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: mannose-6-phosphate receptor, cation dependent [ Homo sapiens ]
• Official Symbol: M6PR
• Synonyms: CD-MPR; MPR 46; MPR-46; MPR46; SMPR
• Gene ID: 4074
• mRNA Refseq: NM_001207024.1
• Protein Refseq: NP_001193953.1
• MIM: 154540
• UniProt ID: P20645