Recombinant Human MACROD2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MACROD2-5233H
• Product Overview: MACROD2 MS Standard C13 and N15-labeled recombinant protein (NP_542407) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 47.2 kDa
• AA Sequence: MYPSNKKKKVWREEKERLLKMTLEE RRKEYLRDYIPLNSILSWKEEMKGK GQNDEENTQETSQVKKSLTEKVSLY RGDITLLEVDAIVNAANASLLGGGG VDGCIHRAAGPCLLAECRNLNGCDT GHAKITCGYDLPAKYVIHTVGPIAR GHINGSHKEDLANCYKSSLKLVKEN NIRSVAFPCISTGIYGFPNEPAAVI ALNTIKEWLAKNHHEVDRIIFCVFL EVDFKIYKKKMNEFFSVDDNNEEEE DVEMKEDSDENGPEEKQSVEEMEEQ SQDADGVNTVTVPGPASEEAVEDCK DEDFAKDENITKGGEVTDHSVRDQD HPDGQENDSTKNEIKIETESQSSYM ETEELSSNQEDAVIVEQPEVIPLTE DQEEKEGEKAPGEDTPRMPGKSEGS SDLENTPGPDAGAQDEAKEQRNGTK TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MACROD2 mono-ADP ribosylhydrolase 2 [ Homo sapiens (human) ]
• Official Symbol: MACROD2
• Synonyms: MACROD2; mono-ADP ribosylhydrolase 2; C2orf133; C20orf133; ADP-ribose glycohydrolase MACROD2; MACRO domain containing 2; MACRO domain-containing protein 2; O-acetyl-ADP-ribose deacetylase MACROD2; [Protein ADP-ribosylaspartate] hydrolase MACROD2; [Protein ADP-ribosylglutamate] hydrolase; [Protein ADP-ribosylglutamate] hydrolase MACROD2
• Gene ID: 140733
• mRNA Refseq: NM_080676
• Protein Refseq: NP_542407
• MIM: 611567
• UniProt ID: A1Z1Q3