Recombinant Human MAD2L1 protein, His-tagged
Cat.No. : | MAD2L1-161H |
Product Overview : | Recombinant Human MAD2L1 (Met1-Asp205) protein was fused to His-tag at C-terminus and expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | Mitotic arrest deficient 2-like protein 1 (MAD2L1) is also known as Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2), MAD2. MAD2L1/MAD2 belongs to the MAD2 family. MAD2L1/MAD2 contains one HORMA domain. MAD2L1 is the component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1/MAD2 is required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Met1 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 24.3 kDa. The protein migrates as 24 kDa under reducing (R) condition (SDS-PAGE). |
Protein length : | Met1-Asp205 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | MAD2L1 |
Official Symbol : | MAD2L1 |
Synonyms : | MAD2L1; MAD2 mitotic arrest deficient-like 1 (yeast); MAD2 (mitotic arrest deficient, yeast, homolog) like 1; mitotic spindle assembly checkpoint protein MAD2A; HSMAD2; MAD2; MAD2-like protein 1; mitotic arrest deficient 2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 |
Gene ID : | 4085 |
mRNA Refseq : | NM_002358 |
Protein Refseq : | NP_002349 |
MIM : | 601467 |
UniProt ID : | Q13257 |
Products Types
◆ Recombinant Protein | ||
MAD2L1-2438R | Recombinant Rhesus Macaque MAD2L1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAD2L1-418C | Recombinant Cynomolgus Monkey MAD2L1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mad2l1-3895M | Recombinant Mouse Mad2l1 Protein, Myc/DDK-tagged | +Inquiry |
MAD2L1-6868H | Recombinant Human MAD2 Mitotic Arrest Deficient-Like 1 (yeast), His-tagged | +Inquiry |
MAD2L1-28857TH | Recombinant Human MAD2L1, His-tagged | +Inquiry |
◆ Lysates | ||
MAD2L1-4570HCL | Recombinant Human MAD2L1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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