Recombinant Human MAG Protein, Fc/His-tagged

• Cat.No.: MAG-2063H
• Product Overview: Recombinant Human MAG/GMA/Siglec-4 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gly20-Pro516) of human MAG/GMA/Siglec-4 (Accession #NP_002352.1) fused with an Fc, 6×His tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc&His
• Protein Length: Gly20-Pro516
• Description: The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
• Form: Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 90% as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: MAG myelin associated glycoprotein [ Homo sapiens ]
• Official Symbol: MAG
• Synonyms: MAG; myelin associated glycoprotein; GMA; myelin-associated glycoprotein; S MAG; sialic acid binding Ig like lectin 4A; SIGLEC 4A; SIGLEC4A; sialic acid binding Ig-like lectin 4A; sialic acid-binding immunoglobulin-like lectin 4A; S-MAG; SIGLEC-4A
• Gene ID: 4099
• mRNA Refseq: NM_001199216
• Protein Refseq: NP_001186145
• MIM: 159460
• UniProt ID: P20916