Recombinant Human MALT1 protein, His/Thioredoxin-tagged


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Recombinant Human MALT1 protein, His/Thioredoxin-tagged

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Cat.No. : MALT1-857H
Product Overview : Recombinant Human MALT1((Gln 2-Ile57) fused with His/Thioredoxin tag at N-terminal was expressed in E. coli.
Description : This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source : E. coli
Species : Human
Tag : His/Thioredoxin
Form : Supplied as a 0.45 µm filtered solution in 50 mM NaH2PO4 (pH 7.4), 0.3 M NaCl, 80 mM imidazole, 6 M urea.
Molecular Mass : 27 kDa (including N-terminal thioredoxin tag)
Purity : ~0.9
Applications : ELISA, EIA, protein-protein interaction studies, Western Blotting, Dot Blotting, Immunoprecipitation, Protein Array
Storage : Upon arrival, the protein may be stored for 2 weeks at 4 centigrade. For long term storage, it is recommended to store at -20 centigrade or -80 centigrade in appropriate aliquots. Avoid repeated freeze-thaw cycles.
Gene Name : MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 [ Homo sapiens ]
Official Symbol : MALT1
Synonyms : MALT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; MLT; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase; caspase-like protein; MALT associated translocation; MALT lymphoma-associated translocation; MALT-lymphoma associated translocation; MLT1; DKFZp434L132;
Gene ID : 10892
mRNA Refseq : NM_006785
Protein Refseq : NP_006776
MIM : 604860
UniProt ID : Q9UDY8
Chromosome Location : 18q21
Pathway : Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Canonical NF-kappaB pathway, organism-specific biosystem; Downstream Signaling Events Of B Cell Receptor (BCR), organism-specific biosystem;
Function : cysteine-type endopeptidase activity; contributes_to kinase activator activity; peptidase activity; protein binding; protein self-association; signal transducer activity; ubiquitin-protein ligase activity;

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