Recombinant Human MALT1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human MALT1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : MALT1-2551H
Product Overview : MALT1 MS Standard C13 and N15-labeled recombinant protein (NP_776216) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 90.9 kDa
AA Sequence : MSLLGDPLQA LPPSAAPTGP LLAPPAGATL NRLREPLLRR LSELLDQAPE GRGWRRLAEL AGSRGRLRLS CLDLEQCSLK VLEPEGSPSL CLLKLMGEKG CTVTELSDFL QAMEHTEVLQ LLSPPGIKIT VNPESKAVLA GQFVKLCCRA TGHPFVQYQW FKMNKEIPNG NTSELIFNAV HVKDAGFYVC RVNNNFTFEF SQWSQLDVCD IPESFQRSVD GVSESKLQIC VEPTSQKLMP GSTLVLQCVA VGSPIPHYQW FKNELPLTHE TKKLYMVPYV DLEHQGTYWC HVYNDRDSQD SKKVEIIIDE LNNLGHPDNK EQTTDQPLAK DKVALLIGNM NYREHPKLKA PLVDVYELTN LLRQLDFKVV SLLDLTEYEM RNAVDEFLLL LDKGVYGLLY YAGHGYENFG NSFMVPVDAP NPYRSENCLC VQNILKLMQE KETGLNVFLL DMCRKRNDYD DTIPILDALK VTANIVFGYA TCQGAEAFEI QHSGLANGIF MKFLKDRLLE DKKITVLLDE VAEDMGKCHL TKGKQALEIR SSLSEKRALT DPIQGTEYSA ESLVRNLQWA KAHELPESMC LKFDCGVQIQ LGFAAEFSNV MIIYTSIVYK PPEIIMCDAY VTDFPLDLDI DPKDANKGTP EETGSYLVSK DLPKHCLYTR LSSLQKLKEH LVFTVCLSYQ YSGLEDTVED KQEVNVGKPL IAKLDMHRGL GRKTCFQTCL MSNGPYQSSA ATSGGAGHYH SLQDPFHGVY HSHPGNPSNV TPADSCHCSR TPDAFISSFA HHASCHFSRS NVPVETTDEI PFSFSDRLRI SEKTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 [ Homo sapiens (human) ]
Official Symbol : MALT1
Synonyms : MALT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; MLT; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase; caspase-like protein; MALT associated translocation; MALT lymphoma-associated translocation; MALT-lymphoma associated translocation; MLT1; DKFZp434L132;
Gene ID : 10892
mRNA Refseq : NM_173844
Protein Refseq : NP_776216
MIM : 604860
UniProt ID : Q9UDY8

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