Recombinant Human MAP2K1 protein, His-tagged

• Cat.No.: MAP2K1-639H
• Product Overview: Recombinant Human MAP2K1 fused with His tag at C-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: 45 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 10% glycerol, 200 mM imidazole, and 3 mM DTT.
• Molecular Mass: 44.3 kDa
• Purity: > 50 %
• Applications: Useful as a substrate of cRAF (RAF1) and other kinases.
• Storage: >6 months at -80 centigrade.

Gene Information

• Gene Name: MAP2K1 mitogen-activated protein kinase kinase 1 [ Homo sapiens ]
• Official Symbol: MAP2K1
• Synonyms: MAP2K1; mitogen-activated protein kinase kinase 1; PRKMK1; dual specificity mitogen-activated protein kinase kinase 1; MAPKK1; MEK1; MEK 1; MAPKK 1; MAPK/ERK kinase 1; MAP kinase kinase 1; ERK activator kinase 1; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); MKK1
• Gene ID: 5604
• mRNA Refseq: NM_002755
• Protein Refseq: NP_002746
• MIM: 176872
• UniProt ID: Q02750
• Chromosome Location: 15q22.1-q22.33
• Pathway: ARMS-mediated activation, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem
• Function: ATP binding; MAP kinase kinase activity; Ras GTPase binding; mitogen-activated protein kinase kinase kinase binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; receptor signaling protein tyrosine phosphatase activity