Recombinant Human MAP2K2 Protein, Myc/DDK-tagged, C13 and N15-labeled
| Cat.No. : | MAP2K2-4024H |
| Product Overview : | MAP2K2 MS Standard C13 and N15-labeled recombinant protein (NP_109587) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
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| Description : | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 44.2 kDa |
| AA Sequence : | MLARRKPVLPALTINPTIAEGPSPT SEGASEANLVDLQKKLEELELDEQQ KKRLEAFLTQKAKVGELKDDDFERI SELGAGNGGVVTKVQHRPSGLIMAR KLIHLEIKPAIRNQIIRELQVLHEC NSPYIVGFYGAFYSDGEISICMEHM DGGSLDQVLKEAKRIPEEILGKVSI AVLRGLAYLREKHQIMHRDVKPSNI LVNSRGEIKLCDFGVSGQLIDSMAN SFVGTRSYMAPERLQGTHYSVQSDI WSMGLSLVELAVGRYPIPPPDAKEL EAIFGRPVVDGEEGEPHSISPRPRP PGRPVSGHGMDSRPAMAIFELLDYI VNEPPPKLPNGVFTPDFQEFVNKCL IKNPAERADLKMLTNHTFIKRSEVE EVDFAGWLCKTLRLNQPGTPTRTAV TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| Gene Name : | MAP2K2 mitogen-activated protein kinase kinase 2 [ Homo sapiens (human) ] |
| Official Symbol : | MAP2K2 |
| Synonyms : | MAP2K2; mitogen-activated protein kinase kinase 2; PRKMK2; dual specificity mitogen-activated protein kinase kinase 2; MEK2; MAPK/ERK kinase 2; MAP kinase kinase 2; ERK activator kinase 2; mitogen-activated protein kinase kinase 2, p45; MKK2; MAPKK2; FLJ26075; |
| Gene ID : | 5605 |
| mRNA Refseq : | NM_030662 |
| Protein Refseq : | NP_109587 |
| MIM : | 601263 |
| UniProt ID : | P36507 |
Products Types
| ◆ Recombinant Protein | ||
| MAP2K2-1353H | Recombinant Human MAP2K2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| MAP2K2-253H | Recombinant Human MAP2K2 Protein, MYC/DDK-tagged | +Inquiry |
| MAP2K2-0226H | Recombinant Human MAP2K2 Protein (E55-V400), Tag Free | +Inquiry |
| MAP2K2-0227H | Recombinant Human MAP2K2 Protein (E55-V400), His tagged | +Inquiry |
| MAP2K2-3216R | Recombinant Rat MAP2K2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| ◆ Lysates | ||
| MAP2K2-613HCL | Recombinant Human MAP2K2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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