Recombinant Human MAP3K13 cell lysate

• Cat.No.: MAP3K13-1055HCL

Specification

• Description: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: MAP3K13 mitogen-activated protein kinase kinase kinase 13 [ Homo sapiens ]
• Official Symbol: MAP3K13
• Synonyms: MAP3K13; mitogen-activated protein kinase kinase kinase 13; leucine zipper bearing kinase; LZK; MEKK13; mixed lineage kinase; leucine zipper-bearing kinase; MLK; MGC133196
• Gene ID: 9175
• mRNA Refseq: NM_001242314
• Protein Refseq: NP_001229243
• MIM: 604915
• UniProt ID: O43283
• Chromosome Location: 3q27
• Pathway: Insulin Signaling, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Signaling events mediated by VEGFR1 and VEGFR2, organism-specific biosystem
• Function: ATP binding; MAP kinase kinase kinase activity; identical protein binding; magnesium ion binding; nucleotide binding; protein binding; protein homodimerization activity; protein kinase binding; protein serine/threonine kinase activity