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Recombinant Human MAPK1 protein(Met1-Ser360), GST-tagged

Cat.No. : MAPK1-7267H
Product Overview : Recombinant Human ERK2 (NP_002736.3) (Met 1-Ser 360) was expressed in Insect Cells, fused with the GST tag at the N-terminus.
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Source : Insect Cells
Species : Human
Tag : N-GST
Protein length : Met1-Ser360
Form : Lyophilized from sterile 50mM Tris, 100mM NaCl, 0.5mM PMSF, 10% Glycerol, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human ERK2/GST chimera consists of 585 amino acids and predicts a molecular mass of 67 kDa as estimated in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 98 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : MAPK1 mitogen-activated protein kinase 1 [ Homo sapiens ]
Official Symbol : MAPK1
Synonyms : MAPK1; mitogen-activated protein kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41mapk; ERK-2; MAPK 2; p42-MAPK; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK;
Gene ID : 5594
mRNA Refseq : NM_002745
Protein Refseq : NP_002736
MIM : 176948
UniProt ID : P28482

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can MAPK1 be used as a biomarker for cancer diagnosis? 12/28/2021

MAPK1 expression and activity levels can be used as biomarkers to assess cancer risk and prognosis.

How can MAPK1 be targeted in drug development for non-cancer conditions? 11/03/2021

MAPK1 inhibitors are being explored for potential use in non-cancer conditions, such as heart disease and neurodegenerative disorders.

In what other clinical conditions is MAPK1 relevant? 01/12/2020

MAPK1 is also implicated in various other diseases, including cardiovascular diseases and neurological disorders.

Are there targeted therapies that inhibit MAPK1 for cancer treatment? 10/27/2018

Yes, there are targeted therapies that aim to inhibit MAPK1, especially in cases where MAPK1 is overactive in cancer cells.

Can MAPK1 be used for personalized medicine approaches? 08/19/2017

Yes, by assessing the MAPK1 status in a patient's cells, healthcare providers can develop personalized treatment plans.

Customer Reviews (3)

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03/24/2022

    Whether it be troubleshooting issues, offering experimental guidance, or addressing any concerns, the manufacturer's technical support ensures that researchers have a reliable and knowledgeable resource to rely on.

    03/26/2021

      In addition to its scientific merits, the manufacturer of MAPK1 protein stands out for its outstanding technical support.

      03/11/2020

        The company provides a dedicated team of experts who are readily available to assist researchers throughout their experimental journey.

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