Recombinant Human MAPK14 Protein, MYC/DDK-tagged

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Recombinant Human MAPK14 Protein, MYC/DDK-tagged

MAPK14 Related Products

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Cat.No. : MAPK14-382H
Product Overview : Recombinant human MAPK14 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 41.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : mitogen-activated protein kinase 14 [ Homo sapiens ]
Official Symbol : MAPK14
Synonyms : CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; p38; p38ALPHA; PRKM14; PRKM15; RK; SAPK2A
Gene ID : 1432
mRNA Refseq : NM_001315.2
Protein Refseq : NP_001306.1
MIM : 600289
UniProt ID : Q16539

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