Recombinant Human MAPK8IP1 Protein, MYC/DDK-tagged
| Cat.No. : | MAPK8IP1-378H |
| Product Overview : | Recombinant human MAPK8IP1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. [provided by RefSeq, May 2011]. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | MYC/DDK |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
| Molecular Mass : | 77.3 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name : | mitogen-activated protein kinase 8 interacting protein 1 [ Homo sapiens ] |
| Official Symbol : | MAPK8IP1 |
| Synonyms : | IB1; JIP-1; JIP1; PRKM8IP |
| Gene ID : | 9479 |
| mRNA Refseq : | NM_005456.3 |
| Protein Refseq : | NP_005447.1 |
| MIM : | 604641 |
| UniProt ID : | Q6NUQ9 |
Products Types
| ◆ Recombinant Protein | ||
| MAPK8IP1-3232R | Recombinant Rat MAPK8IP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
| MAPK8IP1-3436H | Recombinant Human MAPK8IP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
| Mapk8ip1-3946M | Recombinant Mouse Mapk8ip1 Protein, Myc/DDK-tagged | +Inquiry |
| MAPK8IP1-711H | Recombinant Human MAPK8IP1 | +Inquiry |
| MAPK8IP1-3576R | Recombinant Rat MAPK8IP1 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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