Recombinant Human MAPK8IP1 Protein, Myc/DDK-tagged, C13 and N15-labeled
| Cat.No. : | MAPK8IP1-2748H |
| Product Overview : | MAPK8IP1 MS Standard C13 and N15-labeled recombinant protein (NP_005447) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 77.5 kDa |
| AA Sequence : | MAERESGGLGGGAASPPAASPFLGL HIASPPNFRLTHDISLEEFEDEDLS EITDECGISLQCKDTLSLRPPRAGL LSAGGGGAGSRLQAEMLQMDLIDAT GDTPGAEDDEEDDDEERAARRPGAG PPKAESGQEPASRGQGQSQGQSQGP GSGDTYRPKRPTTLNLFPQVPRSQD TLNNNSLGKKHSWQDRVSRSSSPLK TGEQTPPHEHICVSDELSPQSGPAP TTGRGTSTDSPCRRSTATQMAPPGG PPAATPGGRGHSHRDRIHYQADVRL EATEEIYLTPVQRPPDAAEPTSAFL PPTESRMSVSSDPDPAAYPSTAGRP HPSISEEEEGFDCMSSPERAEPPGG GWRGSLGEPPPPPRASLSSDTSALS YDSVKYTLVVDEHAQLELVSLRPCF GDYSDESDSATVYDNCASVSSPYES AIGEEYEEAPRPQPPACLSEDSTPD EPDVHFSKKFLNVFMSGRSRSSSAE SFGLFSCIINGEEQEQTHRAIFRFV PRHEDELELEVDDPLLVELQAEDYW YEAYNMRTGARGVFPAYYAIEVTKE PEHMAALAKNSDWVDQFRVKFLGSV QVPYHKGNDVLCAAMQKIATTRRLT VHFNPPSSCVLEINVRGVKIGVKAD DSQEAKGNKCSHFFQLKNISFCGYH PKNNKYFGFITKHPADNRFACHVFV SEDSTKALAESVGRAFQQFYKQFVE YTCPTEDIYLETRTRPLEQKLISEE DLAANDILDYKDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| Gene Name : | MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 [ Homo sapiens (human) ] |
| Official Symbol : | MAPK8IP1 |
| Synonyms : | MAPK8IP1; mitogen-activated protein kinase 8 interacting protein 1; IB1; JIP1; JIP-1; PRKM8IP; C-Jun-amino-terminal kinase-interacting protein 1; IB-1; JNK MAP kinase scaffold protein 1; JNK-interacting protein 1; PRKM8 interacting protein; islet-brain 1 |
| Gene ID : | 9479 |
| mRNA Refseq : | NM_005456 |
| Protein Refseq : | NP_005447 |
| MIM : | 604641 |
| UniProt ID : | Q9UQF2 |
Products Types
| ◆ Recombinant Protein | ||
| Mapk8ip1-3946M | Recombinant Mouse Mapk8ip1 Protein, Myc/DDK-tagged | +Inquiry |
| MAPK8IP1-3436H | Recombinant Human MAPK8IP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
| MAPK8IP1-378H | Recombinant Human MAPK8IP1 Protein, MYC/DDK-tagged | +Inquiry |
| MAPK8IP1-3232R | Recombinant Rat MAPK8IP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
| MAPK8IP1-3576R | Recombinant Rat MAPK8IP1 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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