Recombinant Human MARS2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MARS2-5503H
• Product Overview: MARS2 MS Standard C13 and N15-labeled recombinant protein (NP_612404) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3).
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 66.6 kDa
• AA Sequence: MLRTSVLRLLGRTGASRLSLLEDFG PRYYSSGSLSAGDDACDVRAYFTTP IFYVNAAPHIGHLYSALLADALCRH RRLRGPSTAATRFSTGTDEHGLKIQ QAAATAGLAPTELCDRVSEQFQQLF QEAGISCTDFIRTTEARHRVAVQHF WGVLKSRGLLYKGVYEGWYCASDEC FLPEAKVTQQPGPSGDSFPVSLESG HPVSWTKEENYIFRLSQFRKPLQRW LRGNPQAITPEPFHHVVLQWLDEEL PDLSVSRRSSHLHWGIPVPGDDSQT IYVWLDALVNYLTVIGYPNAEFKSW WPATSHIIGKDILKFHAIYWPAFLL GAGMSPPQRICVHSHWTVCGQKMSK SLGNVVDPRTCLNRYTVDGFRYFLL RQGVPNWDCDYYDEKVVKLLNSELA DALGGLLNRCTAKRINPSETYPAFC TTCFPSEPGLVGPSVRAQAEDYALV SAVATLPKQVADHYDNFRIYKALEA VSSCVRQTNGFVQRHAPWKLNWESP VDAPWLGTVLHVALECLRVFGTLLQ PVTPSLADKLLSRLGVSASERSLGE LYFLPRFYGHPCPFEGRRLGPETGL LFPRLDQSRTWLVKAHRTTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MARS2 methionyl-tRNA synthetase 2, mitochondrial [ Homo sapiens (human) ]
• Official Symbol: MARS2
• Synonyms: MARS2; methionyl-tRNA synthetase 2, mitochondrial; MetRS; COXPD25; mtMetRS; methionine--tRNA ligase, mitochondrial; methionine tRNA ligase 2, mitochondrial; methionine--tRNA ligase 2; methionine-tRNA synthetase 2, mitochondrial; EC 6.1.1.10
• Gene ID: 92935
• mRNA Refseq: NM_138395
• Protein Refseq: NP_612404
• MIM: 609728
• UniProt ID: Q96GW9