"MATK" Related Products


Recombinant Human MATK Protein, GST-tagged

Cat.No.: MATK-50H
Product Overview: Full-length recombinant human MATK (CTK) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: MATK belongs to tyrosine protein kinase family, CSK subfamily. It inactivates Src family kinase activity by specifically phosphorylating their C-terminal regulatory tyrosine residue and may plays a significant role in the signal transduction of hematopoietic cells. MATK binds to the phosphorylated Tyr568/570 sites on c-KIT to which FYN binds and leads to the down-regulation of FYN. MATK has been shown to be involved in signaling in some cases of breast cancer.
Source: Insect cells
Species: Human
Tag : GST
Molecular Mass: ~83 kDa
Applications: KA, WB
Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Gene Name: MATK megakaryocyte-associated tyrosine kinase [ Homo sapiens (human) ]
Official Symbol: MATK megakaryocyte-associated tyrosine kinase [ Homo sapiens (human) ]
Synonyms: CHK; CTK; HHYLTK; HYL; HYLTK; LSK; MATK; megakaryocyte-associated tyrosine kinase; megakaryocyte-associated tyrosine-protein kinase; CSK homologous kinase; Csk-homologous kinase; Csk-type protein tyrosine kinase; HYL tyrosine kinase; hematopoietic consensus tyrosine-lacking kinase; hydroxyaryl-protein kinase; leukocyte carboxyl-terminal src kinase related; protein kinase HYL; tyrosine kinase MATK; tyrosine-protein kinase CTK; tyrosylprotein kinase; EC
Gene ID: 4145
mRNA Refseq: NM_002378
Protein Refseq: NP_002369
MIM: 600038
UniProt ID: P42679

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