Recombinant Human MATK Protein, GST-tagged
Cat.No. : | MATK-50H |
Product Overview : | Full-length recombinant human MATK (CTK) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | MATK belongs to tyrosine protein kinase family, CSK subfamily. It inactivates Src family kinase activity by specifically phosphorylating their C-terminal regulatory tyrosine residue and may plays a significant role in the signal transduction of hematopoietic cells. MATK binds to the phosphorylated Tyr568/570 sites on c-KIT to which FYN binds and leads to the down-regulation of FYN. MATK has been shown to be involved in signaling in some cases of breast cancer. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Molecular Mass : | ~83 kDa |
Applications : | KA, WB |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Storage Buffer : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Gene Name : | MATK megakaryocyte-associated tyrosine kinase [ Homo sapiens (human) ] |
Official Symbol : | MATK megakaryocyte-associated tyrosine kinase [ Homo sapiens (human) ] |
Synonyms : | CHK; CTK; HHYLTK; HYL; HYLTK; LSK; MATK; megakaryocyte-associated tyrosine kinase; megakaryocyte-associated tyrosine-protein kinase; CSK homologous kinase; Csk-homologous kinase; Csk-type protein tyrosine kinase; HYL tyrosine kinase; hematopoietic consensus tyrosine-lacking kinase; hydroxyaryl-protein kinase; leukocyte carboxyl-terminal src kinase related; protein kinase HYL; tyrosine kinase MATK; tyrosine-protein kinase CTK; tyrosylprotein kinase; EC 2.7.10.2 |
Gene ID : | 4145 |
mRNA Refseq : | NM_002378 |
Protein Refseq : | NP_002369 |
MIM : | 600038 |
UniProt ID : | P42679 |
Products Types
◆ Recombinant Protein | ||
MATK-3253R | Recombinant Rat MATK Protein, His (Fc)-Avi-tagged | +Inquiry |
Matk-3970M | Recombinant Mouse Matk Protein, Myc/DDK-tagged | +Inquiry |
Matk-1767M | Recombinant Mouse Matk Protein, His&GST-tagged | +Inquiry |
MATK-5451H | Recombinant Human Megakaryocyte-Associated Tyrosine Kinase, His-tagged | +Inquiry |
MATK-5386M | Recombinant Mouse MATK Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MATK-4450HCL | Recombinant Human MATK 293 Cell Lysate | +Inquiry |
MATK-4451HCL | Recombinant Human MATK 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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