"MATK" Related Products

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Recombinant Human MATK Protein, GST-tagged

Cat.No. : MATK-50H
Product Overview : Full-length recombinant human MATK (CTK) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : MATK belongs to tyrosine protein kinase family, CSK subfamily. It inactivates Src family kinase activity by specifically phosphorylating their C-terminal regulatory tyrosine residue and may plays a significant role in the signal transduction of hematopoietic cells. MATK binds to the phosphorylated Tyr568/570 sites on c-KIT to which FYN binds and leads to the down-regulation of FYN. MATK has been shown to be involved in signaling in some cases of breast cancer.
Source : Insect cells
Species : Human
Tag : GST
Molecular Mass : ~83 kDa
Applications : KA, WB
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Storage Buffer : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Specific Activity :

Purity :

Gene Name : MATK megakaryocyte-associated tyrosine kinase [ Homo sapiens (human) ]
Official Symbol : MATK megakaryocyte-associated tyrosine kinase [ Homo sapiens (human) ]
Synonyms : CHK; CTK; HHYLTK; HYL; HYLTK; LSK; MATK; megakaryocyte-associated tyrosine kinase; megakaryocyte-associated tyrosine-protein kinase; CSK homologous kinase; Csk-homologous kinase; Csk-type protein tyrosine kinase; HYL tyrosine kinase; hematopoietic consensus tyrosine-lacking kinase; hydroxyaryl-protein kinase; leukocyte carboxyl-terminal src kinase related; protein kinase HYL; tyrosine kinase MATK; tyrosine-protein kinase CTK; tyrosylprotein kinase; EC 2.7.10.2
Gene ID : 4145
mRNA Refseq : NM_002378
Protein Refseq : NP_002369
MIM : 600038
UniProt ID : P42679

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