Recombinant Human Matrix Metallopeptidase 9
Cat.No. : | MMP9-709H |
Product Overview : | Recombinant human matrix metallopeptidase 9 was expressed inNSO Cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MMP9-709H |
Description : | Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases and tumor invasion. MMPs are synthesized as enzymogen and converted to active form by other MMPs or extracellular proteinases. MMP9, also known as 92-kDa gelatinase B/type IV collagenase, is secreted from neutrophils, macrophages, and a number of transformed cells, and is the most complex family member in terms of domain structure and regulation of its activity. It contains a fibronectin-like domain, which functions in the binding of gelatin, a unique serine/proline/threonine-rich collagen type V-like domain probably serving as attachment sites of multiple O-linked oligosaccharides and a carboxyl terminal hemopexin-like domain. This enzyme degrades various substrates including gelatin, collagen types IV and V, and elastin. |
Source : | Mammalian cells |
Assay : | >95% (SDS-PAGE). |
Form : | Buffered aqueous solution. |
Mol wt : | Apparent mol wt ~93 kDa. |
Shipped In : | Dry ice. |
Storage Temp : | −70℃. |
Personal Protective Equipment : | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
Gene Name : | MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) [ Homo sapiens ] |
Synonyms : | MMP9; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); GELB; CLG4B; MMP-9; MANDP2; MMP-9; EC 3.4.24.35; OTTHUMP00000031674; 92 kDa gelatinase 3; 92 kDa type IV collagenase; Gelatinase B; macrophage gelatinase 2; type V collagenase |
Gene ID : | 4318 |
mRNA Refseq : | NM_004994 |
Protein Refseq : | NP_004985 |
MIM : | 120361 |
UniProt ID : | P14780 |
Chromosome Location : | 20q12-q13 |
Pathway : | Bladder cancer; Pathways in cancer; Leukocyte transendothelial migration |
Function : | calcium ion binding; collagen binding; metalloendopeptidase activity; peptidase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
Mmp9-10596M | Recombinant Mouse Mmp9 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mmp9-1788M | Recombinant Mouse Mmp9 Protein, His&GST-tagged | +Inquiry |
MMP9-2451H | Recombinant Human MMP9 Protein, His-tagged | +Inquiry |
MMP9-801H | Recombinant Human MMP9 Protein, His-tagged | +Inquiry |
MMP9-661H | Active Recombinant Human MMP9 protein(Met1-Asp707) | +Inquiry |
◆ Native Protein | ||
MMP9-9810 | Active Native Human MMP9 | +Inquiry |
MMP9-40H | Native Human MMP-9/Lipocalin/TIMP-1 Complex | +Inquiry |
MMP9-41H | Native Human MMP-9/TIMP-1 Complex | +Inquiry |
◆ Lysates | ||
MMP9-1940RCL | Recombinant Rat MMP9 cell lysate | +Inquiry |
MMP9-2560HCL | Recombinant Human MMP9 cell lysate | +Inquiry |
MMP9-2026MCL | Recombinant Mouse MMP9 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2130 | MMP-9 Inhibitor Screening Kit | +Inquiry |
Kit-3100 | MMP-9 Fluorimetric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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