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Recombinant Human MBD4 protein, T7/His-tagged

Cat.No. : MBD4-224H
Product Overview : Recombinant human MBD4 cDNA (580aa) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
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Source : E. coli
Species : Human
Tag : T7/His
Form : 0.25 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.
AA Sequence : MASMTGGQQMGRGHHHHHHENLYFQ GGEFGTTGLESLSLGDRGAAPTVTS SERLVPDPPNDLRKEDVAMELERVG EDEEQMMIKRSSECNPLLQEPIASA QFGATAGTECRKSVPCGWERVVKQR LFGKTAGRFDVYFISPQGLKFRSKS SLANYLHKNGETSLKPEDFDFTVLS KRGIKSRYKDCSMAALTSHLQNQSN NSNWNLRTRSKCKKDVFMPPSSSSE LQESRGLSNFTSTHLLLKEDEGVDD VNFRKVRKPKGKVTILKGIPIKKTK KGCRKSCSGFVQSDSKRESVCNKAD AESEPVAQKSQLDRTVCISDAGACG ETLSVTSEENSLVKKKERSLSSGSN FCSEQKTSGIINKFCSAKDSEHNEK YEDTFLESEEIGTKVEVVERKEHLH TDILKRGSEMDNNCSPTRKDFTGEK IFQEDTIPRTQIERRKTSLYFSSKY NKEALSPPRRKAFKKWTPPRSPFNL VQETLFHDPWKLLIATIFLNRTSGK MAIPVLWKFLEKYPSAEVARTADWR DVSELLKPLGLYDLRAKTIVKFSDE YLTKQWKYPIELHGIGKYGNDSYRI FCVNEWKQVHPEDHKLNKYHDWLWE NHEKLSLS
Purity : >90% by SDS-PAGE
Storage : Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days.
Gene Name : MBD4 methyl-CpG binding domain protein 4 [ Homo sapiens ]
Official Symbol : MBD4
Synonyms : MBD4; methyl-CpG binding domain protein 4; methyl-CpG-binding domain protein 4; MED1; G/T mismatch glycosylase; G/U mismatch glycosylase; methyl-CpG-binding protein MBD4; 3,N(4)-ethenocytosine glycosylase; methyl-CpG-binding endonuclease 1; mismatch-specific DNA N-glycosylase; putative methyl-CpG binding protein; G/5-fluorouracil mismatch glycosylase with biphasic kinetics;
Gene ID : 8930
mRNA Refseq : NM_003925
Protein Refseq : NP_003916
MIM : 603574
UniProt ID : O95243
Chromosome Location : 3q21.3
Pathway : Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged pyrimidine, organism-specific biosystem; DNA Repair, organism-specific biosystem;
Function : DNA binding; catalytic activity; endodeoxyribonuclease activity; hydrolase activity; protein binding; satellite DNA binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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