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Recombinant Human MCM8 Protein, GST-tagged

Cat.No. : MCM8-4516H
Product Overview : Human MCM8 full-length ORF (BAG37214.1, 1 a.a. - 840 a.a.) recombinant protein with GST tag at N-terminal.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 118.8 kDa
AA Sequence : MNGEYRGRGFGRGRFQSWKRGRGGG NFSGKWREREHRPDLSKTTGKRTSE QTPQFLLSTKTPQSMQSTLDRFIPY KGWKLYFSEVYSDSSPLIEKIQAFE KFFTRHIDLYDKDEIERKGSILVDF KELTEGGEVTNLIPDIATELRDAPE KTLACMGLAIHQVLTKDLERHAAEL QAQEGLSNDGETMVNVPHIHARVYN YEPLTQLKNVRANYYGKYIALRGTV VRVSNIKPLCTKMAFLCAACGEIQS FPLPDGKYSLPTKCPVPVCRGRSFT ALRSSPLTVTMDWQSIKIQELMSDD QREAGRIPRTIECELVHDLVDSCVP GDTVTITGIVKVSNAEEGSRNKNDK CMFLLYIEANSISNSKGQKTKSSED GCKHGMLMEFSLKDLYAIQEIQAEE NLFKLIVNSLCPVIFGHELVKAGLA LALFGGSQKYADDKNRIPIRGDPHI LVVGDPGLGKSQMLQAACNVAPRGV YVCGNTTTTSGLTVTLSKDSSSGDF ALEAGALVLGDQGICGIDEFDKMGN QHQALLEAMEQQSISLAKAGVVCSL PARTSIIAAANPVGGHYNKAKTVSE NLKMGSALLSRFDLVFILLDTPNEH HDHLLSEHVIAIRAGKQRTISSATV ARMNSQDSNTSVLEVVSEKPLSERL KVVPGETIDPIPHQLLRKYIGYARQ YVYPRLSTEAARVLQDFYLELRKQS QRLNSSPITTRQLESLIRLTEARAR LELREEATKEDAEDIVEIMKYSMLG TYSDEFGNLDFERSQHGSGMSNRST AKRFISALNNVAERTYNNIFQFHQL RQIAKELNIQVADFENFIGSLNDQG YLLKKGPKVYQLQTM
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : MCM8 minichromosome maintenance complex component 8 [ Homo sapiens ]
Official Symbol : MCM8
Synonyms : MCM8; minichromosome maintenance complex component 8; C20orf154, chromosome 20 open reading frame 154; DNA replication licensing factor MCM8; dJ967N21.5; MGC4816; MGC12866; MGC119522; MGC119523; REC; REC homolog (Drosophila); REC homolog; minichromosome maintenance 8; MCM8 minichromosome maintenance deficient 8; C20orf154;
Gene ID : 84515
mRNA Refseq : NM_032485
Protein Refseq : NP_115874
MIM : 608187
UniProt ID : Q9UJA3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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