Recombinant Human MED31 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MED31-2587H
• Product Overview: MED31 MS Standard C13 and N15-labeled recombinant protein (NP_057144) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 15.8 kDa
• AA Sequence: MAAAVAMETDDAGNRLRFQLELEFV QCLANPNYLNFLAQRGYFKDKAFVN YLKYLLYWKDPEYAKYLKYPQCLHM LELLQYEHFRKELVNAQCAKFIDEQ QILHWQHYSRKRMRLQQALAEQQQQ NNTSGKTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MED31 mediator complex subunit 31 [ Homo sapiens (human) ]
• Official Symbol: MED31
• Synonyms: MED31; mediator complex subunit 31; mediator of RNA polymerase II transcription, subunit 31 homolog (S. cerevisiae); mediator of RNA polymerase II transcription subunit 31; CGI 125; Soh1; hSOH1; mediator complex subunit SOH1; mediator of RNA polymerase II transcription, subunit 31 homolog; CGI-125; 3110004H13Rik; FLJ27436; FLJ36714
• Gene ID: 51003
• mRNA Refseq: NM_016060
• Protein Refseq: NP_057144
• UniProt ID: Q9Y3C7