Recombinant Human MEF2A Protein, GST-tagged

• Cat.No.: MEF2A-4462H
• Product Overview: Human MEF2A full-length ORF ( AAH13437, 1 a.a. - 499 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes agamous and deficiens and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.41 kDa
• AA Sequence: MGRKKIQITRIMDERNRQVTFTKRK FGLMKKAYELSVLCDCEIALIIFNS SNKLFQYASTDMDKVLLKYTEYNEP HESRTNSDIVEALNKKEHRGCDSPD PDTSYVLTPHTEEKYKKINEEFDNM MRNHKIAPGLPPQNFSMSVTVPVTS PNALSYTNPGSSLVSPSLAASSTLT DSSMLSPPQTTLHRNVSPGAPQRPP STGNAGGMLSTTDLTVPNGAGSSPV GNGFVNSRASPNLIGATGANSLGKV MPTKSPPPPGGGNLGMNSRRPDLRV VIPPSSKGMMPPLNTQRISSSQATQ PLATPVVSVTTPSLPPQGLVYSAMP TAYNTDYSLTSADLSALQGFNSPGM LSLGQVSAWQQHHLGQAALSSLVAG GQLSQGSNLSINTNQNISIKSEPIS PPRDRMTPSGFQQQQQQQQQQQPPP PPQPQPQPPQPQPRQEMGRSPVDSL SSSSSSYDGSDREDPRGDFHSPIVL GRPPNTEDRESPSVKRMRMDAWVT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MEF2A myocyte enhancer factor 2A [ Homo sapiens ]
• Official Symbol: MEF2A
• Synonyms: MEF2A; myocyte enhancer factor 2A; myocyte-specific enhancer factor 2A; serum response factor-like protein 1; MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A); mef2; ADCAD1; RSRFC4; RSRFC9
• Gene ID: 4205
• mRNA Refseq: NM_001130926
• Protein Refseq: NP_001124398