Recombinant Full Length Human MEF2A Protein, C-Flag-tagged

• Cat.No.: MEF2A-1842HFL
• Product Overview: Recombinant Full Length Human MEF2A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 53.7 kDa
• AA Sequence: MGRKKIQITRIMDERNRQVTFTKRK FGLMKKAYELSVLCDCEIALIIFNS SNKLFQYASTDMDKVLLKYT EYNEPHESRTNSDIVEALNKKEHRG CDSPDPDTSYVLTPHTEEKYKKINE EFDNMMRNHKIAPGLPPQNF SMSVTVPVTSPNALSYTNPGSSLVS PSLAASSTLTDSSMLSPPQTTLHRN VSPGAPQRPPSTGNAGGMLS TTDLTVPNGAGSSPVGNGFVNSRAS PNLIGATGANSLGKVMPTKSPPPPG GGNLGMNSRKPDLRVVIPPS SKGMMPPLNTQRISSSQATQPLATP VVSVTTPSLPPQGLVYSAMPTAYNT DYSLTSADLSALQGFNSPGM LSLGQVSAWQQHHLGQAALSSLVAG GQLSQGSNLSINTNQNISIKSEPIS PPRDRMTPSGFQQQQQQQQQ QQPPPPPQPQPQPPQPQPRQEMGRS PVDSLSSSSSSYDGSDREDPRGDFH SPIVLGRPPNTEDRESPSVK RMRMDAWVT SGPTRTRRLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transcription Factors

Gene Information

• Gene Name: MEF2A myocyte enhancer factor 2A [ Homo sapiens (human) ]
• Official Symbol: MEF2A
• Synonyms: mef2; ADCAD1; RSRFC4; RSRFC9
• Gene ID: 4205
• mRNA Refseq: NM_005587.6
• Protein Refseq: NP_005578.2
• MIM: 600660
• UniProt ID: Q02078