Recombinant Human MET Protein, DYKDDDDK-tagged
Cat.No. : | MET-151H |
Product Overview : | Recombinant Human MET proto-oncogene, receptor tyrosine kinase(MET) protein, transcript variant 2(NM_000245), with a DYKDDDDK tag, was expressed in human cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. |
Source : | Human cells |
Species : | Human |
Tag : | DYKDDDDK |
Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.306, without any preservatives. |
Molecular Mass : | 153 kDa |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
Gene Name : | MET met proto-oncogene (hepatocyte growth factor receptor) [ Homo sapiens ] |
Official Symbol : | MET |
Synonyms : | MET; met proto-oncogene (hepatocyte growth factor receptor); hepatocyte growth factor receptor; HGFR; RCCP2; SF receptor; HGF receptor; oncogene MET; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase; AUTS9; c-Met; |
Gene ID : | 4233 |
mRNA Refseq : | NM_000245 |
Protein Refseq : | NP_000236 |
MIM : | 164860 |
UniProt ID : | P08581 |
Products Types
◆ Recombinant Protein | ||
MET-1139M | Recombinant Mouse MET protein(Met1-Asn929), His-tagged | +Inquiry |
Met-4417R | Active Recombinant Rat Met Protein | +Inquiry |
MET-3309R | Recombinant Rat MET Protein, His (Fc)-Avi-tagged | +Inquiry |
MET-4419H | Recombinant Human MET Protein, GST-tagged | +Inquiry |
MET-1176C | Recombinant Cynomolgus/Rhesus MET protein(Met1-Thr932) | +Inquiry |
◆ Lysates | ||
MET-001CCL | Recombinant Cynomolgus MET cell lysate | +Inquiry |
MET-2047MCL | Recombinant Mouse MET cell lysate | +Inquiry |
MET-1054RCL | Recombinant Rat MET cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0550 | Met Kinase (Human) Assay/Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket