Recombinant Human MET Protein, GST/His-tagged

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Recombinant Human MET Protein, GST/His-tagged

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Cat.No. : MET-4420H
Product Overview : Human MET (NM_000245.2, 956 a.a. - 1390 a.a.) partial recombinant protein with GST-His tag expressed in Sf9 cells.
Description : The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Source : Insect cell
Species : Human
Tag : GST/His
Form : Liquid
Bio-activity : 105 pmol/μg x min
Molecular Mass : 78.788 kDa
AA Sequence : KKRKQIKDLG SELVRYDARV HTPHLDRLVS ARSVSPTTEM VSNESVDYRA TFPEDQFPNS SQNGSCRQVQ YPLTDMSPIL TSGDSDISSP LLQNTVHIDL SALNPELVQA VQHVVIGPSS LIVHFNEVIG RGHFGCVYHG TLLDNDGKKI HCAVKSLNRI TDIGEVSQFL TEGIIMKDFS HPNVLSLLGI CLRSEGSPLV VLPYMKHGDL RNFIRNETHN PTVKDLIGFG LQVAKAMKYL ASKKFVHRDL AARNCMLDEK FTVKVADFGL ARDMYDKEYY SVHNKTGAKL PVKWMALESL QTQKFTTKSD VWSFGVVLWE LMTRGAPPYP DVNTFDITVY LLQGRRLLQP EYCPDPLYEV MLKCWHPKAE MRPSFSELVS RISAIFSTFI GEHYVHVNAT YVNVKCVAPY PSLLSSEDNA DDEVDTRPAS FWETS
Applications : Functional Study
SDS-PAGE
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration : 0.144 μg/μL
Storage Buffer : In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
Quality Control Testing :

2 μg/lane SDS-PAGE Stained with Coomassie Blue

Result of activity analysis :

Gene Name : MET met proto-oncogene (hepatocyte growth factor receptor) [ Homo sapiens ]
Official Symbol : MET
Synonyms : MET; met proto-oncogene (hepatocyte growth factor receptor); hepatocyte growth factor receptor; HGFR; RCCP2; SF receptor; HGF receptor; oncogene MET; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase; AUTS9; c-Met;
Gene ID : 4233
mRNA Refseq : NM_000245
Protein Refseq : NP_000236
MIM : 164860
UniProt ID : P08581

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