Recombinant Human MGME1 Protein, MYC/DDK-tagged

• Cat.No.: MGME1-1239H
• Product Overview: Recombinant human MGME1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 39.2 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: mitochondrial genome maintenance exonuclease 1 [ Homo sapiens ]
• Official Symbol: MGME1
• Synonyms: bA504H3.4; C20orf72; DDK1; MTDPS11
• Gene ID: 92667
• Protein Refseq: NP_443097
• MIM: 615076