Recombinant Human MIA, His-tagged

• Cat.No.: MIA-5001H
• Product Overview: Recombinant human MIA protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MIA belongs to the MIA/OTOR family and contains 1 SH3 domain. This protein elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
• Molecular Mass: 14.4 kDa (128aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGPMPKLADR KLCADQECSH PISMAVALQD YMAPDCRFLT IHRGQVVYVF SKLKGRGRLF WGGSVQGDYY GDLAARLGYF PSSIVREDQT LKPGKVDVKT DKWDFYCQ
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: MIA melanoma inhibitory activity [ Homo sapiens ]
• Official Symbol: MIA
• Synonyms: MIA; melanoma inhibitory activity; melanoma-derived growth regulatory protein; CD RAP; CD-RAP
• Gene ID: 8190
• mRNA Refseq: NM_001202553
• Protein Refseq: NP_001189482
• MIM: 601340
• UniProt ID: Q16674
• Chromosome Location: 19q13.32-q13.33
• Function: growth factor activity