Recombinant Human MIB2 protein, His & T7-tagged

• Cat.No.: MIB2-1884H
• Product Overview: Recombinant Human MIB2 aa. (Thr687~Leu930 (Accession # Q96AX9)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Thr687~Leu930
• Description: The protein encoded by this gene is an E3 ubiquitin protein ligase that mediates ubiquitination of proteins in the Notch signaling pathway. The encoded protein may be a suppressor of melanoma invasion.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.4kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 7.9

Gene Information

• Gene Name: MIB2 mindbomb E3 ubiquitin protein ligase 2 [ Homo sapiens (human) ]
• Official Symbol: MIB2
• Synonyms: MIB2; mindbomb E3 ubiquitin protein ligase 2; ZZZ5; ZZANK1; E3 ubiquitin-protein ligase MIB2; RING-type E3 ubiquitin transferase MIB2; mind bomb homolog 2; mindbomb homolog 2; novel zinc finger protein; novelzin; putative NF-kappa-B-activating protein 002N; skeletrophin; zinc finger ZZ type with ankyrin repeat domain protein 1; zinc finger, ZZ type with ankyrin repeat domain 1
• Gene ID: 142678
• mRNA Refseq: NM_001170686.1
• Protein Refseq: NP_001164157.1
• UniProt ID: Q96AX9