Recombinant Human MICA Protein, His (Fc)-Avi-tagged

• Cat.No.: MICA-202H
• Product Overview: Recombinant Human MICA with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: MICA MHC class I polypeptide-related sequence A [ Homo sapiens ]
• Official Symbol: MICA
• Synonyms: MICA; MHC class I polypeptide-related sequence A; PERB11.1; HLA class I antigen; stress inducible class I homolog; MHC class I chain-related protein A; MIC-A; FLJ36918; FLJ60820; MGC21250; MGC111087
• Gene ID: 100507436
• mRNA Refseq: NM_000247
• Protein Refseq: NP_000238
• MIM: 600169
• UniProt ID: Q29983

Reviews

01/16/2022

when utilized in Western Blotting experiments, the MICA protein has consistently produced distinct and well-defined protein bands, facilitating clear and accurate interpretation of results.

01/18/2020

I have successfully implemented the MICA protein in protein electron microscopy structure analysis, where its attributes have greatly aided in elucidating complex molecular structures.

03/23/2016

Considering its remarkable performance across multiple assays, I wholeheartedly endorse the usage of the MICA protein in various research studies.

Q&As

How does MICA relate to infectious diseases?

MICA expression can change during viral infections and influence the immune response to the pathogen.

How can MICA protein be targeted in cancer therapy?

Monoclonal antibodies and immunotherapies can target MICA on cancer cells, making them more susceptible to immune system attack.

Are there diagnostic tests that measure MICA expression in cancer patients?

Yes, tests like immunohistochemistry and flow cytometry can measure MICA expression on tumor cells and help in cancer diagnosis and treatment planning.

What are the implications of MICA expression in autoimmune diseases?

Altered MICA expression has been associated with some autoimmune diseases, such as rheumatoid arthritis, suggesting a potential role in disease development.

Can MICA polymorphisms affect the outcome of organ transplantation?

Yes, MICA polymorphisms can influence the success of organ transplantation by affecting the compatibility between donor and recipient.