Recombinant Human MICU1 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: MICU1-279H
• Product Overview: CBARA1 MS Standard C13 and N15-labeled recombinant protein (NP_006068) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 54.4 kDa
• AA Sequence: MFRLNSLSALAELAVGSRWYHGGSQ PIQIRRRLMMVAFLGASAVTASTGL LWKRAHAESPPCVDNLKSDIGDKGK NKDEGDVCNHEKKTADLAPHPEEKK KKRSGFRDRKVMEYENRIRAYSTPD KIFRYFATLKVISEPGEAEVFMTPE DFVRSITPNEKQPEHLGLDQYIIKR FDGKKISQEREKFADEGSIFYTLGE CGLISFSDYIFLTTVLSTPQRNFEI AFKMFDLNGDGEVDMEEFEQVQSII RSQTSMGMRHRDRPTTGNTLKSGLC SALTTYFFGADLKGKLTIKNFLEFQ RKLQHDVLKLEFERHDPVDGRITER QFGGMLLAYSGVQSKKLTAMQRQLK KHFKEGKGLTFQEVENFFTFLKNIN DVDTALSFYHMAGASLDKVTMQQVA RTVAKVELSDHVCDVVFALFDCDGN GELSNKEFVSIMKQRLMRGLEKPKD MGFTRLMQAMWKCAQETAWDFALPK QTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MICU1 mitochondrial calcium uptake 1 [ Homo sapiens (human) ]
• Official Symbol: MICU1
• Synonyms: MICU1; mitochondrial calcium uptake 1; calcium binding atopy related autoantigen 1, CBARA1; calcium uptake protein 1, mitochondrial; CALC; EFHA3; FLJ12684; ara CALC; atopy related autoantigen; atopy-related autoantigen CALC; calcium binding atopy-related autoantigen 1; calcium-binding atopy-related autoantigen 1; CBARA1; DKFZp564C246
• Gene ID: 10367
• mRNA Refseq: NM_006077
• Protein Refseq: NP_006068
• MIM: 605084
• UniProt ID: Q9BPX6