Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2, His-tagged
| Cat.No. : | MAP4K2-1263H |
| Product Overview : | Recombinant human full length MAP4K2,His-tagged is expressed in Insect cells. |
- Specification
- Gene Information
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| Cat. No. : | MAP4K2-1263H | ||
| Description : | MAP4K2 is an enzymethat in humans is encoded by the MAP4K2 gene. The protein encoded by thisgene is a member of the serine/threonine protein kinase family. Although thiskinase is found in many tissues, its expression in lymphoid follicles isrestricted to the cells of germinal centre, where it may participate inB-cell differentiation. This kinase can be activated by TNF-alpha, and hasbeen shown to specifically activate MAP kinases. This kinase is also found tointeract with TNF receptor-associated factor 2 (TRAF2), which is involved inthe activation of MAP3K1/MEKK1. | ||
| Source : | Insect cells | ||
| Species : | Human | ||
| Form : | Liquid in50 mM Tris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mMDTT + 50% glycerol. | ||
| Molecular Weight : | 95.6 kDa | ||
| Concentration : | 0.42mg/ml | ||
| Specific Activity : | 728 nmole of phosphate transferred tomyelin basic protein (MBP) per minute per mg of total protein at 30°C.Activity determined at a final protein concentration of 3.33 μg/ml. | ||
| Storage : | Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles. | ||
| OfficialSymbol : | MAP4K2 | ||
| nullValue_other : |
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| Gene Name : | MAP4K2 mitogen-activated protein kinase kinase kinase kinase2 [ Homo sapiens ] |
| Synonyms : | MAP4K2; mitogen-activated protein kinasekinase kinase kinase 2; RAB8IP; BL44; GCK; OTTHUMP00000042793; OTTHUMP00000069727;OTTHUMP00000069728; OTTHUMP00000199616; OTTHUMP00000199613; OTTHUMP00000199614;OTTHUMP00000199615; EC 2.7.11.1; B lymphocyte serine/threonine-protein kinase;Germinal center kinase; GC kinase; MAPK/ERK kinase kinase 2; MEK kinasekinase 2; MEKKK2; Rab8-interacting protein; B lymphocyte serine/threonine proteinkinase; germinal centre kinase (GC kinase); EC 2.7.11; Rab8 interactingprotein; Germinal centre kinase |
| Gene ID : | 5871 |
| mRNA Refseq : | NM_004579 |
| Protein Refseq : | NP_004570 |
| MIM : | 603166 |
| UniProt ID : | Q12851 |
| Chromosome Location : | 11q13.1 |
| Pathway : | MAPK signalingpathway; InsulinSignaling; TNF receptor signaling pathway |
Products Types
| ◆ Recombinant Protein | ||
| MAP4K2-5338M | Recombinant Mouse MAP4K2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| Map4k2-3933M | Recombinant Mouse Map4k2 Protein, Myc/DDK-tagged | +Inquiry |
| MAP4K2-387H | Recombinant Human MAP4K2 Protein, MYC/DDK-tagged | +Inquiry |
| MAP4K2-28743TH | Recombinant Human MAP4K2 | +Inquiry |
| MAP4K2-3782Z | Recombinant Zebrafish MAP4K2 | +Inquiry |
| ◆ Lysates | ||
| MAP4K2-626HCL | Recombinant Human MAP4K2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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