Recombinant Human MLANA, GST-tagged

• Cat.No.: MLANA-2040H
• Product Overview: The protein was expressed as gst-tagged fusion protein by E.Coli and puri?ed by GSH-sepharose.

Specification

• Description: Protein melan-A also known as melanoma antigen recognized by T-cells 1 orMART-1 is a proteinthat in humans is encoded by the MLANAgene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class Icomplexes which present it to T cells of the immune system. These complexes can be found on the surface ofmelanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
• Protein length: 1-118aa
• Storage: The protein is stored in PBS bu?er at -20 oC. Repeated freeze thaw cycles should be avoided.

Gene Information

• Gene Name: MLANA melan-A [ Homo sapiens (human) ]
• Official Symbol: MLANA
• Synonyms: MLANA; MART1; MART-1; melan-A; melanoma antigen recognized by T-cells 1; antigen LB39-AA; antigen SK29-AA; protein Melan-A
• Gene ID: 2315
• mRNA Refseq: NM_005511
• Protein Refseq: NP_005502
• MIM: 605513
• UniProt ID: Q16655
• Chromosome Location: 9p24.1
• Function: protein binding