Recombinant Human MLLT3 Protein, GST-tagged

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Recombinant Human MLLT3 Protein, GST-tagged

MLLT3 Related Products

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Cat.No. : MLLT3-5392H
Product Overview : Human MLLT3 full-length ORF ( AAH36089, 1 a.a. - 568 a.a.) recombinant protein with GST-tag at N-terminal.
Description : MLLT3 (MLLT3, Super Elongation Complex Subunit) is a Protein Coding gene. Diseases associated with MLLT3 include Acute Myeloid Leukemia With T(9;11)(P22;Q23) and Myeloid/Lymphoid Or Mixed Lineage Leukemia. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and Transcriptional misregulation in cancer. An important paralog of this gene is MLLT1.
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 88 kDa
AA Sequence : MASSCAVQVK LELGHRAQVR KKPTVEGFTH DWMVFVRGPE HSNIQHFVEK VVFHLHESFP RPKRVCKDPP YKVEESGYAG FILPIEVYFK NKEEPRKVRF DYDLFLHLEG HPPVNHLRCE KLTFNNPTED FRRKLLKAGG DPNRSIHTSS SSSSSSSSSS SSSSSSSSSS SSGSSSSSSS SSSSSSSSSS TSFSKPHKLM KEHKEKPSKD SREHKSAFKE PSRDHNKSSK ESSKKPKENK PLKEEKIVPK MAFKEPKPMS KEPKPDSNLL TITSGQDKKA PSKRPPISDS EELSAKKRKK SSSEALFKSF SSAPPLILTC SADKKQIKDK SHVKMGKVKI ESETSEKKKS TLPPFDDIVD PNDSDVEENI SSKSDSEQPS PASSSSSSSS SFTPSQTRQQ GPLRSIMKDL HSDDNEEESD EVEDNDNDSE MERPVNRGGS RSRRVSLSDG SDSESSSASS PLHHEPPPPL LKTNNNQILE VKSPIKQSKS DKQIKNGECD KAYLDELVEL HRRLMTLRER HILQQIVNLI EETGHFHITN TTFDFDLCSL DKTTVRKLQS YLETSGTS
Applications : Antibody Production
Functional Study
Compound Screening
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 [ Homo sapiens ]
Official Symbol : MLLT3
Synonyms : MLLT3; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3; myeloid/lymphoid or mixed lineage leukemia (trithorax (Drosophila) homolog); translocated to, 3; protein AF-9; AF 9; AF9; YEATS3; YEATS domain-containing protein 3; ALL1-fused gene from chromosome 9 protein; myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3; FLJ2035;
Gene ID : 4300
mRNA Refseq : NM_004529
Protein Refseq : NP_004520
MIM : 159558
UniProt ID : P42568

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