Recombinant Human MMAA Protein, GST-tagged

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Recombinant Human MMAA Protein, GST-tagged

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Cat.No. : MMAA-5403H
Product Overview : Human MMAA full-length ORF ( NP_758454.1, 1 a.a. - 418 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 72.9 kDa
AA Sequence : MPMLLPHPHQ HFLKGLLRAP FRCYHFIFHS STHLGSGIPC AQPFNSLGLH CTKWMLLSDG LKRKLCVQTT LKDHTEGLSD KEQRFVDKLY TGLIQGQRAC LAEAITLVES THSRKKELAQ VLLQKVLLYH REQEQSNKGK PLAFRVGLSG PPGAGKSTFI EYFGKMLTER GHKLSVLAVD PSSCTSGGSL LGDKTRMTEL SRDMNAYIRP SPTRGTLGGV TRTTNEAILL CEGAGYDIIL IETVGVGQSE FAVADMVDMF VLLLPPAGGD ELQGIKRGII EMADLVAVTK SDGDLIVPAR RIQAEYVSAL KLLRKRSQVW KPKVIRISAR SGEGISEMWD KMKDFQDLML ASGELTAKRR KQQKVWMWNL IQESVLEHFR THPTVREQIP LLEQKVLIGA LSPGLAADFL LKAFKSRD
Applications : Antibody Production
Functional Study
Compound Screening
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : MMAA methylmalonic aciduria (cobalamin deficiency) cblA type [ Homo sapiens ]
Official Symbol : MMAA
Synonyms : MMAA; methylmalonic aciduria (cobalamin deficiency) cblA type; methylmalonic aciduria (cobalamin deficiency) type A; methylmalonic aciduria type A protein, mitochondrial; cblA; MGC120010; MGC120011; MGC120012; MGC120013;
Gene ID : 166785
mRNA Refseq : NM_172250
Protein Refseq : NP_758454
MIM : 607481
UniProt ID : Q8IVH4

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